Aerosols Handbook: Measurement, Dosimetry, and Health by Lev S. Ruzer, Naomi H. Harley

By Lev S. Ruzer, Naomi H. Harley

With the speedy development of the nanotechnology undefined, the necessity to comprehend the organic results of aerosol publicity has develop into more and more vital. that includes contributions via major specialists within the box, Aerosols instruction manual: size, Dosimetry, and healthiness results, moment Edition bargains an up to date review of many points of aerosols, from houses to future health results and epidemiology.

Covering indoor, open air, business, clinical, pharmaceutical, and radioactive aerosols, this ebook explores aerosol dosimetry by way of defining phrases reminiscent of publicity and dose. moreover, it appears at nanometer debris, the mechanism of aerosol deposition within the lungs, and modeling deposition with a corresponding uncertainty in chance review. The textual content additionally emphasizes the significance of exact aerosol measurements, relatively respiring quarter publicity assessments.

Examining radioactive aerosols, the booklet discusses classes discovered from nuclear injuries, radon and thoron, and long-lived radionuclides within the surroundings. It brings jointly learn on either radioactive and nonradioactive aerosols, delivering readers with a extra whole view of ways aerosols behave within the lungs.

New during this Edition

  • Five new chapters that deal with the protection of nanomaterials, facing nanoparticle mobile penetration, excessive point ratio nanomaterials, nanoaerosols in drug supply, chance evaluate, and future health effects
  • New chapters on atmospheric toxins regarding weather switch, chemical analyses of particle filter out deposits, and classical nucleation theory
  • New info on size, dosimetry, and healthiness effects

Updated all through, this moment version remains to be a vital source in the event you learn publicity, dosages, and toxicity to strengthen remedies for publicity, lessen pollution, and determine larger protection rules, fairly in industries utilizing nanotechnologies.

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Extra resources for Aerosols Handbook: Measurement, Dosimetry, and Health Effects

Sample text

Coarse spray delivery to a localized region of the pulmonary airways for gene therapy. Human Gene Therapy 11, 361–371 (2000). 137. Dolovich, M. New propellant-free technologies under investigation. Journal of Aerosol Medicine 12(Suppl. 1), S9–S17 (1999). 138. J. and Swift, D. Characterization of pharmaceutical and diagnostic aerosols. A. and Willeke, K. eds. Aerosol Measurement: Principles, Techniques and Applications. Wiley: New York, pp. 1031–1052 (2001). 139. Finnin, B. and Morgan, T. Transdermal penetration enhancers: Applications, limitations, and potential.

Drug Development and Industrial Pharmacy 34, 948–959 (2008). 90. Peart, J. J. New developments in dry powder inhaler technology. American Pharmaceutical Review 14, 37–45 (2001). 91. J. A. Therapeutic uses of lung aerosols. Inhalation Aerosols: Physical and Biological Basis for Therapy 94, 233–269 (1996). 92. Taburet, A. and Schmit, B. Pharmacokinetic optimisation of asthma treatment. Clinical Pharmacokinetics 26, 396–418 (1994). 93. Ilowite, J. Techniques of aerosol therapy. Emergency Medicine 23(7), 68–76 (1991).

Lancet 375, 706–708 (2010). 45. Burger, J. et al. Stabilizing formulations for inhalable powders of live-attenuated measles virus vaccine. Journal of Aerosol Medicine and Pulmonary Drug Delivery 21, 25–34 (2008). 46. Shi, S. and Hickey, A. 4-Ag85B. Pharmaceutical Research 27, 350–360 (2010). 47. Corbett, M. et al. Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic. Proceedings of the National Academy of Sciences of the United States of America 105, 2046–2051 (2008).

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