By Peter S. Harper
An eminent geneticist, veteran writer, OMMG sequence Editor, and famous archivist, Peter Harper provides a full of life account of ways our rules and information approximately human genetics have built during the last century from the point of view of somebody contained in the box with a deep curiosity in its historic elements. Dr. Harper has researched the heritage of genetics and has had own touch with a bunch of key figures whose thoughts and stories expand again 50 years, and he has interviewed and recorded conversations with a lot of those vital geneticists. therefore, instead of being a standard background, this publication transmits the essence of the tips and the folk concerned and the way they interacted in advancing- and occasionally retarding- the sector. From the origins of human genetics; during the contributions of Darwin, Mendel, and different giants; the id of the 1st human chromosome abnormalities; and up during the of entirety of the Human Genome venture, this Short History is written within the author's attribute transparent and private type, which appeals to geneticists and to all these attracted to the tale of human genetics.
Read or Download A Short History of Medical Genetics PDF
Similar special topics books
In the course of global battle II, mother Chung's used to be where to be in San Francisco. infantrymen, motion picture stars, and politicians collected at her domestic to socialise, to teach their commitment to the Allied reason, and to precise their affection for Dr. Margaret Chung (1889-1959). the 1st identified American-born chinese language woman doctor, Chung proven one of many first Western clinical clinics in San Francisco's Chinatown within the Nineteen Twenties.
A. Cornelius Celsus was once writer, most likely throughout the reign of the Roman Emperor Tiberius (14–37 CE), of a normal encyclopaedia of agriculture, drugs, army arts, rhetoric, philosophy, and jurisprudence, in that order of matters. Of all this nice paintings there survives in simple terms the eight books on medication (De Medicina).
On July 17, 2012, the centenary of Henri Poincare's loss of life used to be honored; his identify being linked to such a lot of fields of information that he used to be regarded as the final Universalist. In natural and utilized arithmetic, Physics, Astronomy, Engineering and Philosophy, his works have had an outstanding effect around the globe.
A spouse to technological know-how, expertise, and medication in historic Greece and Rome brings a clean standpoint to the research of those disciplines within the historic international, with 60 chapters analyzing those issues from a number of serious and technical views. Brings a clean standpoint to the learn of technology, know-how, and medication within the historical international, with 60 chapters reading those subject matters from quite a few serious and technical views starts off insurance in six hundred BCE and comprises sections at the later Roman Empire and past, that includes dialogue of the transmission and reception of those principles into the Renaissance Investigates key disciplines, innovations, and events in historical technological know-how, expertise, and medication in the historic, cultural, and philosophical contexts of Greek and Roman society Organizes its content material in halves: the 1st specializes in mathematical and typical sciences; the second one specializes in cultural functions and interdisciplinary subject matters 2 Volumes
Additional info for A Short History of Medical Genetics
Darwin’s work, in which human examples are mixed in with comparable observations on dogs, cattle, pigeons, and plants, provides an early illustration of another important theme in the development of human and medical genetics: the universality of genetic processes. This principle was ﬁrst recognized when Camerarius (see later discussion) discovered sexual processes Before Mendel in plants in 1694. From the outset, workers in genetics, including medical geneticists, have moved easily between species, often using evidence from one species to support an argument relating to another.
Osler himself reported a number of new conditions, including hereditary hemorrhagic telangiectasia, although he was less concerned with the possible underlying hereditary mechanisms than with the clinical aspects. McKusick (1976) described Osler’s contributions in his paper, Osler as a Medical Geneticist. Not all of these early reports on inherited disease showed the multigenerational transmission pattern characteristic of autosomal dominant inheritance. F I G U R E 1–3 (A) George Huntington (1850–1916).
Mendel Gregor Mendel (Fig. 1−19) never worked or wrote on problems of human inheritance, nor indeed on that of any animal species; his breeding studies were entirely conﬁned to plants. It is unlikely that this was the result of any conscious or speciﬁc restriction related to his being based in a monastic setting; rather, the policy of his order and its enlightened abbot, Cyrill Knapp, was to place his religious community at the forefront of agricultural improvement and scientiﬁc thought for the beneﬁt of the local population.